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The exact progression as to styles and their changes is an on-going topic of discussion among Featherweight collectors.
This may be due to when and where they were constructed in the various Singer factories.
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The Roman encyclopedist Celsus, in his De Medicina of ca.
30 AD, suggested willow leaf extract to treat the four signs of inflammation: redness, heat, swelling and pain.
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Aspirin's popularity declined after the development of acetaminophen/paracetamol in 1956 and ibuprofen in 1962.
In the 1960s and 1970s, John Vane and others discovered the basic mechanism of aspirin's effects, Willow bark preparations became a standard part of the materia medica of Western medicine beginning at least with the Greek physician Hippocrates in the fifth century BC; he recommended chewing on willow bark to relieve pain or fever, and drinking tea made from it to relieve pain during childbirth.
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in the second half of the nineteenth century, other academic chemists established the compound's chemical structure and devised more efficient methods of synthesis.